A 42 year old female with multiple ailments

I've been given this case to solve in an attempt to understand the topic of patient clinical data analysis to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and come up with a diagnosis and treatment plan

You can find the entire real patient technical problem in this link here:

https://classworkdecjan.blogspot.com/2019/05/42-f-with-severe-regular-edema-with_17.html?m=1

Following is my analysis of this patients problem:

when she was born she had jaundice which was the suspicion of hemolysis at birth. Associated with some congenital defects suspecting G6PD deficiency because of:

1) sleeplessness which might have occurred because of lack of glycine- improved on taking serine which is a precursor of glycine

2) exacerbation symptoms after consumption of fava beans (Favism)

3) antimalarial drugs causing hemolysis

produced NADPH general logical symptoms because of increased oxidative stress or because of excess baravin is found in G6PD deficiency.

She was prone to infections throughout her life.

The muscle dysfunction which developed later in life might be due to AMPD1 deficiency- ribose has changed her daily ability to function.

Disturbances maybe because of AMPD1 deficiency also

kidney needs lots of energy for ions active transport and has water balance in body and age salt as when you might be losing them heavily- must have caused abdominal distention (Edema)